tert-Butyl hydroperoxide → HCID 46834505, compound

Participants

Reaction Steps

According to a similar procedure to that described in Example 1-(10), [8-[(tert-butyldimethylsilyl)oxymethyl]-1-naphthyl]methanol (described in Aust. J. Chem., 49, 793 (1996); 4.04 g, 13.4 mmol), tetrazole (2.34 g, 33.4 mmol), bis(allyloxy)(diisopropylamino)phosphine (described in Tetrahedron Lett., 30, 4219 (1989); 3.93 g, 16.0 mmol), and tert-butyl hydroperoxide (80% di-tert-butyl peroxide solution; Merck; 1.8 g, 16 mmol) were reacted, and the reaction mixture was worked up to afford, after extraction, an oily residue. The residue was subjected to chromatography on a silica gel (120 g) column (eluent; ethyl acetate:hexane=1:5˜1:2) to afford the title compound (5.02 g, 81% yield) as a colorless oil.

Provenance & Evidence