Water → HCID 46834506, compound

Participants

Reaction Steps

To a solution of diallyl [8-[(tert-butyldimethylsilyl)oxymethyl]-1-naphthyl]methyl phosphate (5.01 g, 10.8 mmol) obtained from Example 25-(1) in tetrahydrofuran (50 ml) was added tetrabutylammonium fluoride (1 mol/l tetrahydrofuran solution; 13.5 ml, 13.5 mmol), and the mixture was stirred at room temperature for 1 hour. Water was added and the product was extracted with ethyl acetate. The organic layer was concentrated under reduced pressure to give an oily residue. The residue was subjected to chromatography on a silica gel (75 g) column (eluent; ethyl acetate:hexane=3:1˜4:1) to afford the title compound (2.22 g, 59% yield) as a colorless oil.

Provenance & Evidence