tert-Butyl hydroperoxide → HCID 46834796, compound

Participants

Reaction Steps

[4-[(tert-Butyldimethylsilyl)oxymethyl]-3-furyl]methanol (174 mg, 0.72 mmol) obtained from Example 35-(1) was reacted in dichloromethane (3 ml) with tetrazole (61 mg, 0.87 mmol), bis(allyloxy)(diisopropylamino)phosphine (265 mg, 1.08 mmol), and tert-butyl hydroperoxide (80% di-tert-butyl peroxide solution; Merck; 135 mg, 1.2 mmol) according to a similar procedure to that described in Example 1-(10). The oily residue obtained by extraction was subjected to chromatography on a silica gel (5 g) column (eluent; ethyl acetate:hexane=1:4) to afford the title compound (273 mg, 93% yield) as a colorless oil.

Provenance & Evidence