Ammonia → Tegafur

Participants

Reaction Steps

The wet cake from Step A is charged to a mixing tank containing de-ionized water under sustained agitation to completely disperse the TS-1 crystals. This takes approximately 20 to 60 minutes. The pH is measured and adjusted with aqueous ammonia to a value of 9.5. The typical pH of TS-1 wet cake with tetrapropylammonium template in water is approximately 9. Aqueous tetraammine palladium nitrate is added to the mixing tank and the contents are agitated for 30 minutes while monitoring the pH. Sufficient tetraammine palladium nitrate is used to provide 0.1 wt % Pd on the TS-1. The TS-1 crystal slurry is transferred to Step C.

Provenance & Evidence