Formaldehyde → HCID 11329935, compound

HRID 1766995Notes

Reaction equation

[F:1][CH:2]([NH:32][CH:33]1[CH2:37][CH2:36][N:35]([CH3:38])[CH2:34]1)[C:3]1[CH:8]=[CH:7][C:6]([C:9]([NH:11][C:12]2[CH:17]=[CH:16][C:15]([CH3:18])=[C:14]([NH:19][C:20]3[N:25]=[C:24]([C:26]4[CH:27]=[N:28][CH:29]=[CH:30][CH:31]=4)[CH:23]=[CH:22][N:21]=3)[CH:13]=2)=[O:10])=[CH:5][CH:4]=1.[CH2:39]=O>>[F:1][CH:2]([N:32]([CH3:39])[CH:33]1[CH2:37][CH2:36][N:35]([CH3:38])[CH2:34]1)[C:3]1[CH:8]=[CH:7][C:6]([C:9]([NH:11][C:12]2[CH:17]=[CH:16][C:15]([CH3:18])=[C:14]([NH:19][C:20]3[N:25]=[C:24]([C:26]4[CH:27]=[N:28][CH:29]=[CH:30][CH:31]=4)[CH:23]=[CH:22][N:21]=3)[CH:13]=2)=[O:10])=[CH:5][CH:4]=1

Participants

Reactant 2

HCID 712Formaldehyde

HCID 11237572HCID 11237572, compound

Product 1

HCID 11329935HCID 11329935, compound

Procedure

The product from Example 11 was methylated via reductive amination with HCHO/NaBHCN afforded the title compound. Mass: (M+1), 526.

Sources & evidence

ORD record: ord-519171dac6ed4d0b924d48d29ae70dbf
Source dataset: uspto-grants-2007_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07232825B2

Reaction notes

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