Acetaldehyde → HCID 11168458, compound

HRID 1766997Notes

Reaction equation

[F:1][CH:2]([N:32]1[CH2:37][CH2:36][NH:35][CH2:34][CH2:33]1)[C:3]1[CH:8]=[CH:7][C:6]([C:9]([NH:11][C:12]2[CH:17]=[CH:16][C:15]([CH3:18])=[C:14]([NH:19][C:20]3[N:25]=[C:24]([C:26]4[CH:27]=[N:28][CH:29]=[CH:30][CH:31]=4)[CH:23]=[CH:22][N:21]=3)[CH:13]=2)=[O:10])=[CH:5][CH:4]=1.[CH3:38][CH:39]=O>>[CH2:38]([N:35]1[CH2:34][CH2:33][N:32]([CH:2]([F:1])[C:3]2[CH:8]=[CH:7][C:6]([C:9]([NH:11][C:12]3[CH:17]=[CH:16][C:15]([CH3:18])=[C:14]([NH:19][C:20]4[N:25]=[C:24]([C:26]5[CH:27]=[N:28][CH:29]=[CH:30][CH:31]=5)[CH:23]=[CH:22][N:21]=4)[CH:13]=3)=[O:10])=[CH:5][CH:4]=2)[CH2:37][CH2:36]1)[CH3:39]

Participants

Reactant 2

HCID 177Acetaldehyde

HCID 11477506HCID 11477506, compound

Product 1

HCID 11168458HCID 11168458, compound

Procedure

The product from Example 3 was ethylated via reductive amination with CH3CHO/NaBHCN afforded the title compound. Mass: (M+1), 526.

Sources & evidence

ORD record: ord-36e993fcec9f44e2a7a0d125c1d1984c
Source dataset: uspto-grants-2007_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07232825B2

Reaction notes

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