反应详情

In a 50 mL volume glass vessel equipped with a stirrer and a thermometer were placed 5.0 g (29.1 mmol) of 4-chloroanthranilic acid and 20 mL (156 mmol) of 15 wt. % ammonia methanol solution. The reaction was carried out for 2 hours at room temperature. After the reaction was complete, the reaction mixture was concentrated under reduced pressure, to obtain 5.0 g (isolated yield: 95%) of ammonium 4-chloroanthranilate as white solid.

1. customIn a 50 mL volume glass vessel equipped with a stirrer
2. concentrationthe reaction mixture was concentrated under reduced pressure