反应详情

3-[2-(2-Benzyloxyphenyl)-cyclopent-1-enyl] benzoic acid ethyl ester (120 mg) was refluxed for 1 h in methanol/2N sodium hydroxide (10/10 mL). The reaction mixture was then evaporated down to 3 mL on a rotary evaporator. 2N Hydrochloric acid was added. The product was extracted with dichloromethane (2×10 mL), dried over magnesium sulphate and evaporated down to an oil which solidified on standing (wt: 100 mg).

1. customThe reaction mixture was then evaporated down to 3 mL on a rotary evaporator
2. addition2N Hydrochloric acid was added
3. extractionThe product was extracted with dichloromethane (2×10 mL)
4. dry with materialdried over magnesium sulphate
5. customevaporated down to an oil which