HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(4-Fluorobenzyloxy)-5-trifluoromethylphenylboronic acid → 3-{2-[5-Trifluoromethyl-2-(4-fluorobenzyloxy)phenyl]cyclopent-1-enyl}-6-aminobenzoic Acid Ethyl Ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(4-Fluorobenzyloxy)-5-trifluoromethylphenylboronic acid | HCID 21112921 | — |
| Reactant | 3-(2-Bromocyclopent-1-enyl)-6-aminobenzoic acid ethyl ester | HCID 69507797 | — |
| Product | 3-{2-[5-Trifluoromethyl-2-(4-fluorobenzyloxy)phenyl]cyclopent-1-enyl}-6-aminobenzoic Acid Ethyl Ester | HCID 69507902 | — |
Reaction Steps
Prepared by general procedure C(iii) but using 2-(4-fluorobenzyloxy)-5-trifluoromethylphenylboronic acid instead of 2-(benzyloxy)-5-chlorophenylboronic acid and 3-(2-bromocyclopent-1-enyl)-6-aminobenzoic acid ethyl ester instead of 3-(2-bromo-cyclopent-1-enyl)-6-methylbenzoic acid ethyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07232821B2 |
| Source dataset | uspto-grants-2007_06 |
| ORD ID | ord-49d3c15181be48b5bee315d1d748d73c |
| Source note | uspto-grants-2007_06 |