Acetyl chloride → HCID 69507814, compound

HRID 1767232Notes

Reaction equation

[C:1](Cl)(=[O:3])[CH3:2].[CH2:5]([O:7][C:8](=[O:36])[C:9]1[C:14]([NH2:15])=[CH:13][CH:12]=[C:11]([C:16]2[CH2:20][CH2:19][CH2:18][C:17]=2[C:21]2[CH:26]=[C:25]([CH3:27])[CH:24]=[CH:23][C:22]=2[O:28][CH2:29][C:30]2[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=2)[CH:10]=1)[CH3:6]>>[CH2:5]([O:7][C:8](=[O:36])[C:9]1[C:14]([NH:15][C:1](=[O:3])[CH3:2])=[CH:13][CH:12]=[C:11]([C:16]2[CH2:20][CH2:19][CH2:18][C:17]=2[C:21]2[CH:26]=[C:25]([CH3:27])[CH:24]=[CH:23][C:22]=2[O:28][CH2:29][C:30]2[CH:31]=[CH:32][CH:33]=[CH:34][CH:35]=2)[CH:10]=1)[CH3:6]

Participants

Reactant 2

HCID 6367Acetyl chloride

HCID 69507674HCID 69507674, compound

Product 1

HCID 69507814HCID 69507814, compound

Procedure

Prepared by general procedure E but using acetyl chloride instead of propionyl chloride and 3-{2-[5-methyl-2-(benzyloxy)phenyl]cyclopent-1-enyl}-6-aminobenzoic acid ethyl ester instead of 5-[2-(2-benzyloxy-5-chlorophenyl)-cyclopent-1-enyl]-2-aminobenzoic acid methyl ester.

Workup

customPrepared by general procedure E

Sources & evidence

ORD record: ord-cd2d629041a64b41ab62803f04735594
Source dataset: uspto-grants-2007_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07232821B2

Reaction notes

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