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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1767245Generated: November 3, 2026

Acetone → 6-{2-[5-Fluoro-2-(benzyloxy)phenyl]cyclopent-1-enyl}-pyridine-2-carboxylic Acid Benzyl Ester

https://huagongshe.com/reaction/1767245

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetoneHCID 180—
ReactantMethyl Ethyl KetoneHCID 6569—
ReactantBenzyl BromideHCID 7498—
ReactantHCID 135979826HCID 135979826—
Product6-{2-[5-Fluoro-2-(benzyloxy)phenyl]cyclopent-1-enyl}-pyridine-2-carboxylic Acid Benzyl EsterHCID 69508202—

Reaction Steps

Prepared by general procedure 5 but using 6-{2-[5-fluoro-2-(hydroxy)phenyl]cyclopent-1-enyl}pyridine-2-carboxylic acid instead of 6-{2-[5-chloro-2-(hydroxy)phenyl]cyclopent-1-enyl}pyridine-2-carboxylic acid, benzyl bromide instead of 4-chlorobenzyl bromide and with acetone as solvent instead of 2-butanone.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07232821B2
Source datasetuspto-grants-2007_06
ORD IDord-6bfa40dfcf3746768878974c17913e71
Source noteuspto-grants-2007_06