HuagongsheHuagongshe Chemistry Print Report · For research reference only
[5-Chloro-2-(2,4-di-fluorobenzyloxy)phenyl]boronic acid → 3-{2-[5-Chloro-2-(2,4-difluorobenzyloxy)phenyl]cyclopent-1-enyl}-5-fluorobenzoic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | [5-Chloro-2-(2,4-di-fluorobenzyloxy)phenyl]boronic acid | HCID 21112998 | — |
| Reactant | Ethyl 3-(2-bromocyclopent-1-enyl)-5-fluorobenzoate | HCID 57862528 | — |
| Product | 3-{2-[5-Chloro-2-(2,4-difluorobenzyloxy)phenyl]cyclopent-1-enyl}-5-fluorobenzoic acid ethyl ester | HCID 69508230 | — |
Reaction Steps
Prepared by general procedure B(iii) but using 3-(2-bromocyclopent-1-enyl)-5-fluorobenzoic acid ethyl ester instead of 3-(2-bromo-cyclopent-1-enyl)-6-methylbenzoic acid ethyl ester and using [5-chloro-2-(2,4-di-fluorobenzyloxy)phenyl]boronic acid instead of (5-chloro-2-benzyloxyphenyl)boronic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07232821B2 |
| Source dataset | uspto-grants-2007_06 |
| ORD ID | ord-e40ec17bdcc340548c916e581aa77406 |
| Source note | uspto-grants-2007_06 |