HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(4-Fluorobenzyloxy)-5-trifluoromethylphenylboronic acid → 3-{2-[5-Trifluoromethyl-2-(4-fluorobenzyloxy)phenyl]cyclopent-1-enyl}-5-fluorobenzoic Acid Ethyl Ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(4-Fluorobenzyloxy)-5-trifluoromethylphenylboronic acid | HCID 21112921 | — |
| Reactant | Ethyl 3-(2-bromocyclopent-1-enyl)-5-fluorobenzoate | HCID 57862528 | — |
| Product | 3-{2-[5-Trifluoromethyl-2-(4-fluorobenzyloxy)phenyl]cyclopent-1-enyl}-5-fluorobenzoic Acid Ethyl Ester | HCID 69508287 | — |
Reaction Steps
Prepared by general procedure B(iii) but using 3-(2-bromocyclopent-1-enyl)-5-fluorobenzoic acid ethyl ester instead of 3-(2-bromo-cyclopent-1-enyl)-6-methyl benzoic acid ethyl ester and using [5-trifluoromethyl-2-(4-fluorobenzyloxy)phenyl]boronic acid instead of (5-chloro-2-benzyloxyphenyl)boronic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07232821B2 |
| Source dataset | uspto-grants-2007_06 |
| ORD ID | ord-6d75da1f90914cd39a172bcd5ec15284 |
| Source note | uspto-grants-2007_06 |