HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclohexanecarboxaldehyde → 3-Cyclohexyl-7-(2'-acetamidophenyl)-1,2,3,4-tetrahydro-1,2,4-benzothiadiazine-1,1-dioxide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclohexanecarboxaldehyde | HCID 16275 | — |
| Reactant | 2-Acetamidophenylboronic acid | HCID 2737789 | — |
| Reactant | 2-Amino-5-cyanobenzene-1-sulfonamide | HCID 22323994 | — |
| Product | 3-Cyclohexyl-7-(2'-acetamidophenyl)-1,2,3,4-tetrahydro-1,2,4-benzothiadiazine-1,1-dioxide | HCID 22324010 | — |
Reaction Steps
5-Iodo-2-aminobenzenesulfonamide (see compound 37) was transformed by Method H (using 2-Acetamidophenylboronic acid) and Method G (using cyclohexanecarboxaldehyde). M. p. 245–249° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07235548B2 |
| Source dataset | uspto-grants-2007_06 |
| ORD ID | ord-a34a49b74d8f483ab846968453acb562 |
| Source note | uspto-grants-2007_06 |