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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1767668Generated: October 31, 2026

Cyclohexanecarboxaldehyde → 6-chloro-3-cyclohexyl-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide

https://huagongshe.com/reaction/1767668

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclohexanecarboxaldehydeHCID 16275—
Reactant4-Amino-6-chloro-1,3-benzenedisulfonamideHCID 67136—
Product6-chloro-3-cyclohexyl-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxideHCID 4415597—

Reaction Steps

2-Amino-4-chloro-5-sulfamoylbenzenesulfonamide was transformed by Method G (using cyclohexanecarboxaldehyde). M.p. 274–276° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07235548B2
Source datasetuspto-grants-2007_06
ORD IDord-c41ec74f98ee4769acf0c41263bb91bf
Source noteuspto-grants-2007_06