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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1767913Erstellt: 25. Oktober 2026

Lithium Hydroxide → (6-{2-[5-Methyl-2-(4-trifluoromethyl-phenyl)-thiazol-4-yl]-ethoxy}-indol-1-yl)-acetic acid

https://huagongshe.com/reaction/1767913

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktLithium HydroxideHCID 3939—
Edukt(6-{2-[5-Methyl-2-(4-trifluoromethyl-phenyl)-thiazol-4-yl]-ethoxy}-indol-1-yl)-acetic acid tert-butyl esterHCID 69280206—
Produkt(6-{2-[5-Methyl-2-(4-trifluoromethyl-phenyl)-thiazol-4-yl]-ethoxy}-indol-1-yl)-acetic acidHCID 11317127—

Reaktionsschritte

In analogy to the procedure described in example 2 c], (6-{2-[5-methyl-2-(4-trifluoromethyl-phenyl)-thiazol-4-yl]-ethoxy}-indol-1-yl)-acetic acid tert-butyl ester was treated with LiOH to obtain (6-{2-[5-methyl-2-(4-trifluoromethyl-phenyl)-thiazol-4-yl]-ethoxy}-indol-1-yl)-acetic acid as off-white crystals.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07235572B2
Quelldatensatzuspto-grants-2007_06
ORD IDord-66b5a9439fa0491592a798102b391602
Quellennotizuspto-grants-2007_06