HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Butanaminium, N,N,N-tributyl-, fluoride, hydrate → tert-Butyl (3-chloro-6-hydroxy-1H-indol-1-yl)acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Butanaminium, N,N,N-tributyl-, fluoride, hydrate | HCID 16211673 | — |
| Reactant | [6-(Tert-butyl-dimethyl-silanyloxy)-3-chloro-indol-1-yl]-acetic acid tert-butyl ester | HCID 69283059 | — |
| Product | tert-Butyl (3-chloro-6-hydroxy-1H-indol-1-yl)acetate | HCID 69283057 | — |
Reaction Steps
In analogy to the procedure described in example 3 b], [6-(tert-butyl-dimethyl-silanyloxy)-3-chloro-indol-1-yl]-acetic acid tert-butyl ester was treated with tetrabutylammonium fluoride hydrate to obtain (3-chloro-6-hydroxy-indol-1-yl)-acetic acid tert-butyl ester as colorless gum.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07235572B2 |
| Source dataset | uspto-grants-2007_06 |
| ORD ID | ord-7c9cad1ffbf04caa8ce3c8c6df4c3961 |
| Source note | uspto-grants-2007_06 |