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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1767933Generated: October 26, 2026

Lithium Hydroxide → {6-[2-(4-Methyl-2-phenyl-thiazol-5-yl)-ethoxy]-indol-1-yl}-acetic acid

https://huagongshe.com/reaction/1767933

Reaction equation

Participants

RoleNameHCIDCharge
ReactantLithium HydroxideHCID 3939—
Reactant{6-[2-(4-Methyl-2-phenyl-thiazol-5-yl)-ethoxy]-indol-1-yl}-acetic acid tert-butyl esterHCID 69280396—
Product{6-[2-(4-Methyl-2-phenyl-thiazol-5-yl)-ethoxy]-indol-1-yl}-acetic acidHCID 11406703—

Reaction Steps

In analogy to the procedure described in example 2 c], {6-[2-(4-methyl-2-phenyl-thiazol-5-yl)-ethoxy]-indol-1-yl}-acetic acid tert-butyl ester was treated with LiOH to obtain {6-[2-(4-methyl-2-phenyl-thiazol-5-yl)-ethoxy]-indol-1-yl}-acetic acid as off-white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07235572B2
Source datasetuspto-grants-2007_06
ORD IDord-9bab6fe4082e458f8c5b44920968c3da
Source noteuspto-grants-2007_06