1-Butanaminium, N,N,N-tributyl-, fluoride, hydrate → 3-propyl-1H-indol-6-ol

HRID 1767941Notes

Reaction equation

HRID 1767941 reaction equation
C([Si](C)(C)[N:6]1[C:14]2[C:9](=[CH:10][CH:11]=[C:12]([O:15][Si](C(C)(C)C)(C)C)[CH:13]=2)[C:8]([CH2:23][CH2:24][CH3:25])=[CH:7]1)(C)(C)C.O.[F-].C([N+](CCCC)(CCCC)CCCC)CCC>>[CH2:23]([C:8]1[C:9]2[C:14](=[CH:13][C:12]([OH:15])=[CH:11][CH:10]=2)[NH:6][CH:7]=1)[CH2:24][CH3:25]

Participants

3

Reactant 2

HCID 162116731-Butanaminium, N,N,N-tributyl-, fluoride, hydrateHCID 236144821-(tert-butyl-dimethyl-silanyl)-6-(tert-butyl-dimethyl-silanyloxy)-3-propyl-1H-indole

Product 1

HCID 236144983-propyl-1H-indol-6-ol

Procedure

In analogy to the procedure described in example 3 b], 1-(tert-butyl-dimethyl-silanyl)-6-(tert-butyl-dimethyl-silanyloxy)-3-propyl-1H-indole was treated with tetrabutylammonium fluoride hydrate to obtain 3-propyl-1H-indol-6-ol as white crystals.

Sources & evidence

ORD record
ord-0644ae8e7234405b8ed4659fa0f49fbd
Source dataset
uspto-grants-2007_06
Patent number
US07235572B2

Reaction notes

Loading…