HuagongsheHuagongshe Chemistry Print Report · For research reference only
Butyl iodide → 3-butyl-1-(tert-butyl-dimethyl-silanyl)-5-(tert-butyl-dimethyl-silanyloxy)-1H-indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Butyl iodide | HCID 10962 | — |
| Reactant | 3-bromo-1-(tert-butyl-dimethyl-silanyl)-5-(tert-butyl-dimethyl-silanyloxy)-1H-indole | HCID 23614489 | — |
| Reactant | HCID 178418306 | HCID 178418306 | — |
| Product | 3-butyl-1-(tert-butyl-dimethyl-silanyl)-5-(tert-butyl-dimethyl-silanyloxy)-1H-indole | HCID 23614491 | — |
Reaction Steps
In analogy to the procedure described in example 27 c], 3-bromo-1-(tert-butyl-dimethyl-silanyl)-5-(tert-butyl-dimethyl-silanyloxy)-1H-indole was reacted with 1-iodobutane in the presence of tert-butyllithium to form 3-butyl-1-(tert-butyl-dimethyl-silanyl)-5-(tert-butyl-dimethyl-silanyloxy)-1H-indole as dark brown oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07235572B2 |
| Source dataset | uspto-grants-2007_06 |
| ORD ID | ord-2ddc3fd1580c4d7b8c7b2b46688d53b6 |
| Source note | uspto-grants-2007_06 |