HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Iodide → HCID 69280386, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Iodide | HCID 4875 | — |
| Reactant | Cesium carbonate | HCID 10796 | — |
| Reactant | HCID 23614504 | HCID 23614504 | — |
| Reactant | tert-Butyl (6-hydroxy-1H-indol-1-yl)acetate | HCID 69283069 | — |
| Product | HCID 69280386 | HCID 69280386 | — |
Reaction Steps
In analogy to the procedure described in example 1 a], (6-hydroxy-indol-1-yl)-acetic acid tert-butyl ester (example 6 b]) was reacted with 5-chloromethyl-2-(2,3-difluoro-4-trifluoromethyl-phenyl)-4-methyl-thiazole in the presence of cesium carbonate and potassium iodide to obtain {6-[2-(2,3-difluoro-4-trifluoromethyl-phenyl)-4-methyl-thiazol-5-ylmethoxy]-indol-1-yl}-acetic acid tert-butyl ester as colorless liquid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07235572B2 |
| Source dataset | uspto-grants-2007_06 |
| ORD ID | ord-1167e703ede6473595b611b199bb0997 |
| Source note | uspto-grants-2007_06 |