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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1767985Generated: October 30, 2026

1-Butanaminium, N,N,N-tributyl-, fluoride, hydrate → 6-Hydroxyskatole

https://huagongshe.com/reaction/1767985

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Butanaminium, N,N,N-tributyl-, fluoride, hydrateHCID 16211673—
Reactant1-(tert-butyl-dimethyl-silanyl)-6-(tert-butyl-dimethyl-silanyloxy)-3-methyl-1H-indoleHCID 23614481—
Product6-HydroxyskatoleHCID 13662595—

Reaction Steps

In analogy to the procedure described in example 27 d], 1-(tert-butyl-dimethyl-silanyl)-6-(tert-butyl-dimethyl-silanyloxy)-3-methyl-1H-indole was treated with tetrabutylammonium fluoride hydrate to obtain 3-methyl-1H-indol-6-ol as brown crystals.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07235572B2
Source datasetuspto-grants-2007_06
ORD IDord-ff0e8d993e954042b29c36ac39d63405
Source noteuspto-grants-2007_06