Water → HCID 72976951, compound

Participants

Reaction Steps

A solution of 450 mg (0.72 mmol) [4-(4-[1,2,3]triazol-1-yl-butyl)-phenyl]-{2-[2-(4-pentafluorosulfanyl-phenyl)-vinyl]-oxazol-4-ylmethyl}-carbamic acid tert-butyl ester in 4 ml dichloromethane and 4 ml trifluoroacetic acid was stirred at r.t. for 1 h. Water was added and the mixture neutralized with solid sodium carbonate. The organic phase was separated, washed with water, dried over sodium sulfate and evaporated. The residue was stirred with a little isopropanol, the crystallized material isolated by filtration, washed with ether and dried to give 100 mg (27%) of product.

Provenance & Evidence