HCID 15629469, compound → HCID 22660847, compound

Participants

Reaction Conditions

Reaction Steps

2-(4-Chlorophenyl) 2,2-diphenylacetonitrile was synthesized by carefully triturating 1.50 g (4.8 mmol) of 4-chlorotrityl chloride with 1.00 g (11 mmol) of copper cyanide and the resulting mixture was heated for 4 hours at 150° C. without a solvent. After cooling 50 ml of toluene was added, the mixture was filtered and the filtrate was concentrated in vacuo. The resulting residue was recrystallized from petroleum ether (40–60° C.) to give 0.66 g (45%) of the triarylmethyl acetonitrile derivative.

Provenance & Evidence