p-Fluoronitrobenzene → 1-Fluoro-4-[(4-nitrophenoxy)methyl]benzene

HRID 1768137Notes

Reaction equation

[F:1][C:2]1[CH:9]=[CH:8][C:5]([CH2:6][OH:7])=[CH:4][CH:3]=1.F[C:11]1[CH:16]=[CH:15][C:14]([N+:17]([O-:19])=[O:18])=[CH:13][CH:12]=1>>[F:1][C:2]1[CH:9]=[CH:8][C:5]([CH2:6][O:7][C:11]2[CH:16]=[CH:15][C:14]([N+:17]([O-:19])=[O:18])=[CH:13][CH:12]=2)=[CH:4][CH:3]=1

Participants

Reactant 2

HCID 9590p-Fluoronitrobenzene

HCID 680224-Fluorobenzylic alcohol

Product 1

HCID 9575111-Fluoro-4-[(4-nitrophenoxy)methyl]benzene

Procedure

The title compound is prepared in analogy to Example 3a) from 4-fluorobenzyl alcohol and 4-fluoro-nitrobenzene. Yield: 86% of a yellowish solid. Mp=124–126° C.

Sources & evidence

ORD record: ord-d6a895912c38430ba2a3884b55711953
Source dataset: uspto-grants-2007_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07235581B2

Reaction notes

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