6,6-Dimethyl-5,7-dioxaspiro(2.5)octane-4,8-dione → HCID 23614752, compound

HRID 1768138Notes

Reaction equation

HRID 1768138 reaction equation
[F:1][C:2]1[CH:16]=[CH:15][C:5]([CH2:6][O:7][C:8]2[CH:13]=[CH:12][C:11]([NH2:14])=[CH:10][CH:9]=2)=[CH:4][CH:3]=1.CC1(C)[O:25][C:24](=O)[C:21]2([CH2:23][CH2:22]2)[C:20](=[O:27])[O:19]1>>[F:1][C:2]1[CH:16]=[CH:15][C:5]([CH2:6][O:7][C:8]2[CH:13]=[CH:12][C:11]([N:14]3[CH2:23][CH2:22][CH:21]([C:20]([OH:27])=[O:19])[C:24]3=[O:25])=[CH:10][CH:9]=2)=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 797206,6-Dimethyl-5,7-dioxaspiro(2.5)octane-4,8-dioneHCID 64860214-(4-Fluoro-benzyloxy)-phenylamine

Product 1

HCID 23614752HCID 23614752, compound

Procedure

The title compound is prepared in analogy to Example 3c) from 4-(4-fluoro-benzyloxy)-phenylamine and 6,6-dimethyl-5,7-dioxa-spiro[2,5]octane-4,8-dione. Yield: 56% of a colorless solid. MS: m/e=284.1 (M−CO2).

Sources & evidence

ORD record
ord-3a46317129744adfb5336edc9d5e47b1
Source dataset
uspto-grants-2007_06
Patent number
US07235581B2

Reaction notes

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