HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 69490885, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 4-(Bromomethyl)-1,2-difluorobenzene | HCID 581436 | — |
| Reactant | HCID 69490626 | HCID 69490626 | — |
| Product | HCID 69490885 | HCID 69490885 | — |
Reaction Steps
In an analogous manner to that described in Example 2c), the alkylation of the (S)-[1-(4-hydroxy-phenyl)-2-oxo-pyrrolidin-3-yl]-carbamic acid tert-butyl ester [Example 16 a)] with 3,4-difluorobenzylbromide in presence of potassium carbonate yields the title compound as a white solid; MS: m/e=419 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07235581B2 |
| Source dataset | uspto-grants-2007_06 |
| ORD ID | ord-c0c5feb8b53d4514a507e776d7638f74 |
| Source note | uspto-grants-2007_06 |