HCID 54729466, compound → HCID 54712640, compound

HRID 1768532Notes

Reaction equation

HRID 1768532 reaction equation
[CH2:1]([N:8]1[C:17]2[C:12](=[CH:13][C:14]([O:18]CC3C=CC=CC=3)=[CH:15][CH:16]=2)[C:11]([OH:26])=[CH:10][C:9]1=[O:27])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>[Pd].C(O)(=O)C>[CH2:1]([N:8]1[C:17]2[C:12](=[CH:13][C:14]([OH:18])=[CH:15][CH:16]=2)[C:11]([OH:26])=[CH:10][C:9]1=[O:27])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 1

HCID 54729466HCID 54729466, compound

Product 1

HCID 54712640HCID 54712640, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 176Acetic AcidSolvent

Procedure

1-Benzyl-4-hydroxy-6-benzyloxy-2(1H)-quinolinone (Step (1) of Example 7) was subjected to hydrogenolysis using a palladium catalyst and acetic acid as a solvent to produce 1-benzyl-4,6-dihydroxy-2(1H)-quinolinone.

Sources & evidence

ORD record
ord-05ca0d96d40f447d9a4274a44be84879
Source dataset
uspto-grants-1995_01
Patent number
US05378694

Reaction notes

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