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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 176857Generated: October 31, 2026

Tetrahydrofuran → Tert-butyl 5-[[3,5-bis(trifluoromethyl)phenyl]methyl-cyanoamino]-7-methyl-8-(trifluoromethyl)-2,3,4,5-tetrahydro-1-benzazepine-1-carboxylate

https://huagongshe.com/reaction/176857

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantCyanogen BromideHCID 10476—
ReactantDiisopropylethylamineHCID 81531—
ReactantTert-butyl 5-[[3,5-bis(trifluoromethyl)phenyl]methylamino]-7-methyl-8-(trifluoromethyl)-2,3,4,5-tetrahydro-1-benzazepine-1-carboxylateHCID 72297304—
ProductTert-butyl 5-[[3,5-bis(trifluoromethyl)phenyl]methyl-cyanoamino]-7-methyl-8-(trifluoromethyl)-2,3,4,5-tetrahydro-1-benzazepine-1-carboxylateHCID 72297396—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-7a6385addf6f41eca6ba981ed6ba0c5d
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)