Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
5-Isocyanato-1,3-dioxaindane → 1-[6-(3,4-Methylenedioxyphenylcarbamoyloxy)hexyl]-4-(6-fluoro-1,2-benzisoxazol-3-yl) piperidine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 5-Isocyanato-1,3-dioxaindane | HCID 5223213 | — |
| 반응물 | 3-[1-(1-Hydroxyhex-6-yl]-4-piperidinyl]-6-fluoro-1,2-benzisoxazole | HCID 18948930 | — |
| 생성물 | 1-[6-(3,4-Methylenedioxyphenylcarbamoyloxy)hexyl]-4-(6-fluoro-1,2-benzisoxazol-3-yl) piperidine | HCID 11799031 | 51.8% |
반응 단계
Starting from 3-[1-(1-hydroxyhex-6-yl]-4-piperidinyl]-6-fluoro-1,2-benzisoxazole (270 mg, 0.84 mmol) and 3,4-methylenedioxyphenylisocyanate (297 mg, 1.69 mmol) using the procedure described in example 12B was prepared 210 mg (51.8%) of the title compound as an amorphous solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05378714 |
| 출처 데이터셋 | uspto-grants-1995_01 |
| ORD ID | ord-047b409873fe48d9bbfdd02e700861fb |
| 출처 메모 | uspto-grants-1995_01 |