HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Hydroxybenzaldehyde → 2-(3-Formylphenoxy)acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Hydroxybenzaldehyde | HCID 101 | — |
| Reactant | Chloroacetic Acid | HCID 300 | — |
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Solvent | Sodium Hydroxide | HCID 14798 | — |
| Product | 2-(3-Formylphenoxy)acetic acid | HCID 601895 | — |
Reaction Steps
A solution of 3-hydroxybenzaldehyde and 0.3 mol of chloroacetic acid in 300 ml of 2N sodium hydroxide was refluxed for 6 hours. After cooling, the solution was acidified with hydrochloric acid and the precipitate was filtered off and crystallized from ethyl acetate/petroleum ether 60-80.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05378718 |
| Source dataset | uspto-grants-1995_01 |
| ORD ID | ord-d5c74d9a32a84008947e525cbc08a9ee |
| Source note | uspto-grants-1995_01 |