HCID 54289767, compound → HCID 53778671, compound

HRID 1768650Notes

Reaction equation

HRID 1768650 reaction equation
Br[CH2:2][C:3]1[CH:24]=[CH:23][C:6]2[C:7](=[CH:17][C:18]([O:20][CH2:21][CH3:22])=[O:19])[C:8]3[CH:15]=[C:14]([F:16])[CH:13]=[CH:12][C:9]=3[CH:10]=[CH:11][C:5]=2[CH:4]=1.[CH3:25][C:26]1[N:31]=[C:30]2[NH:32][C:33]([CH2:35][CH3:36])=[N:34][C:29]2=[C:28]([CH3:37])[CH:27]=1>>[CH2:21]([O:20][C:18](=[O:19])[CH:17]=[C:7]1[C:6]2[CH:23]=[CH:24][C:3]([CH2:2][N:32]3[C:30]4=[N:31][C:26]([CH3:25])=[CH:27][C:28]([CH3:37])=[C:29]4[N:34]=[C:33]3[CH2:35][CH3:36])=[CH:4][C:5]=2[CH:11]=[CH:10][C:9]2[CH:12]=[CH:13][C:14]([F:16])=[CH:15][C:8]1=2)[CH3:22]

Participants

3

Reactant 2

HCID 54289767HCID 54289767, compoundHCID 178437439HCID 178437439, compound

Product 1

HCID 53778671HCID 53778671, compoundYield 14%

Procedure

The same procedure as in Step D of Example 1 was repeated using 0.34 g of Compound 4-b and 5,7-dimethyl-2-ethyl-3H-imidazo[4,5-b]pyridine to give 60 mg (14%) of the product.

Sources & evidence

ORD record
ord-13a738fcbcfe48a2a752445bd9f12a43
Source dataset
uspto-grants-1995_01
Patent number
US05378701

Reaction notes

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