Diethyl (cyanomethyl)phosphonate → HCID 19970861, compound

HRID 1768651Notes

Reaction equation

HRID 1768651 reaction equation
[Br:1][C:2]1[C:12]2[CH:11]=[CH:10][C:9]3[CH:13]=[C:14]([CH3:17])[CH:15]=[CH:16][C:8]=3[C:7](=O)[C:6]=2[CH:5]=[CH:4][CH:3]=1.[C:19]([CH2:21]P(=O)(OCC)OCC)#[N:20]>>[Br:1][C:2]1[C:12]2[CH:11]=[CH:10][C:9]3[CH:13]=[C:14]([CH3:17])[CH:15]=[CH:16][C:8]=3[CH:7]([CH2:21][C:19]#[N:20])[C:6]=2[CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 75676Diethyl (cyanomethyl)phosphonateHCID 18998709HCID 18998709, compound

Product 1

HCID 19970861HCID 19970861, compoundYield 69%

Procedure

The same procedure as in Step A of Example 2 was repeated using 0.86 g of 1-bromo-8-methyl-5-oxo-5H-dibenzo[a,d]cycloheptene and 1.4 ml of diethyl (cyanomethyl)phosphonate to give 0.64 g (69%) of the product as an oily substance.

Sources & evidence

ORD record
ord-ceec807ba6584d2ab3c1504ec5097b80
Source dataset
uspto-grants-1995_01
Patent number
US05378701

Reaction notes

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