HCID 54352392, compound → HCID 53764086, compound

HRID 1768653Notes

Reaction equation

HRID 1768653 reaction equation
O[CH2:2][C:3]1[CH:4]=[CH:5][C:6]2[CH:12]([CH:13]([C:19]([O:21][CH2:22][CH3:23])=[O:20])[C:14]([O:16][CH2:17][CH3:18])=[O:15])[C:11]3[CH:24]=[CH:25][CH:26]=[CH:27][C:10]=3[CH2:9][O:8][C:7]=2[CH:28]=1.[CH3:29][C:30]1[N:35]=[C:34]2[NH:36][C:37]([CH2:39][CH3:40])=[N:38][C:33]2=[C:32]([CH3:41])[CH:31]=1>>[CH3:29][C:30]1[N:35]=[C:34]2[N:36]([CH2:2][C:3]3[CH:4]=[CH:5][C:6]4[CH:12]([CH:13]([C:14]([O:16][CH2:17][CH3:18])=[O:15])[C:19]([O:21][CH2:22][CH3:23])=[O:20])[C:11]5[CH:24]=[CH:25][CH:26]=[CH:27][C:10]=5[CH2:9][O:8][C:7]=4[CH:28]=3)[C:37]([CH2:39][CH3:40])=[N:38][C:33]2=[C:32]([CH3:41])[CH:31]=1

Participants

3

Reactant 2

HCID 54352392HCID 54352392, compoundHCID 178437439HCID 178437439, compound

Product 1

HCID 53764086HCID 53764086, compoundYield 31%

Procedure

The same procedures as in Steps C and D of Example 1 were repeated using 367 mg of Compound 23-a and 250 mg of 5,7-dimethyl-2-ethyl-3H-imidazo[4,5-b]pyridine to give 150 mg (31%) of the product as an oily substance.

Sources & evidence

ORD record
ord-61f3e74217f543b285963771b3330f9e
Source dataset
uspto-grants-1995_01
Patent number
US05378701

Reaction notes

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