HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 13294373, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Benzyl succinimido carbonate | HCID 83172 | — |
| Reactant | HCID 12651624 | HCID 12651624 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 13294373 | HCID 13294373 | 55.5% |
Reaction Steps
A solution of 4.64 g of cis-4-amino-2-cyclohexene-1-ol, 10.2 g of N-(benzyloxycarbonyloxy)succinimide and 5.7 ml of triethylamine in DMF is diluted with ether after stirring, washed with saturated sodium chloride solution, dried and concentrated. Chromatography of the residue on silica gel (ethyl acetate/hexane 2:1) gives 5.62 g of benzyl (1RS,4SR)-4-hydroxy-2-cyclohexene-1-carbamate. MS: 156 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05378712 |
| Source dataset | uspto-grants-1995_01 |
| ORD ID | ord-a50edae4b438471d85dabda4e781e2fc |
| Source note | uspto-grants-1995_01 |