HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 176888Generated: October 26, 2026
Sodium ion → 5-Cyclohex-1-enyl-3-[[1-(2,2-difluoro-ethyl)-piperidin-4-yl]-(trans-4-methylcyclohexanecarbonyl)amino]-thiophene-2-carboxylic acid methyl ester
https://huagongshe.com/reaction/176888
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Sodium ion | HCID 923 | — |
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Hydride | HCID 166653 | — |
| Reactant | 1,1-Difluoro-2-iodoethane | HCID 3833565 | — |
| Reactant | 5-Cyclohex-1-enyl-3-[(trans-4-methyl-cyclohexanecarbonyl)-piperidin-4-yl-amino]-thiophene-2-carboxylic acid methyl ester | HCID 57795362 | — |
| Product | 5-Cyclohex-1-enyl-3-[[1-(2,2-difluoro-ethyl)-piperidin-4-yl]-(trans-4-methylcyclohexanecarbonyl)amino]-thiophene-2-carboxylic acid methyl ester | HCID 57795509 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
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| Source dataset | Training data from https://doi.org/10.1039/C8SC04228D (6/10) |
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| ORD ID | ord-35ddc9d4cb714a9f9c5c89bfb31c30e6 |
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| Source note | Training data from https://doi.org/10.1039/C8SC04228D (6/10) |
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