Boron tribromide → 4-[5-(Octyloxy)pyridin-2(1H)-ylidene]cyclohexa-2,5-dien-1-one

Participants

Reaction Conditions

Reaction Steps

To a solution of 11C (100 mg) in dichloromethane, cooled to 0° C., was added a solution of boron tribromide in dichloromethane (1M, 0.76 ml). This solution was stirred at 0° C. for 4 hours, then allowed to stand at 4° C. an additional 16 hrs. The solution was then poured into a saturated sodium bicarbonate solution and extracted with dichloromethane. The combined organic layers were dried over sodium sulfate and the solvent removed in vacuo to give a white solid.

Provenance & Evidence