HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperazine, 1-(1-adamantyl)- → 1-(1-Adamantyl)-4-amidinopiperazine hydroiodide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperazine, 1-(1-adamantyl)- | HCID 35373 | — |
| Reactant | 1-Piperazinecarboxaldehyde | HCID 82191 | — |
| Reactant | S-methylthiouronium iodide | HCID 197812 | — |
| Product | 1-(1-Adamantyl)-4-amidinopiperazine hydroiodide | HCID 18946295 | 72.3% |
Reaction Steps
The title compound was prepared as described for 1-formylpiperazine in Example 1 of the published European patent application No. 39,190, starting with 1-(1-adamantyl)piperazine and S-methyl-isothiourea hydroiodide, mp. 278°-280° C., yield: 72.3 %.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05380724 |
| Source dataset | uspto-grants-1995_01 |
| ORD ID | ord-73472acde6f74bd990200d27ffc51b80 |
| Source note | uspto-grants-1995_01 |