反应详情

16.4 g of 2-amino-6-methylbenzothiazole was dissolved in 500 ml of chloroform. To this solution was added dropwise 16.0 g of bromine dissolved in 10 ml of chloroform at room temperature. The reaction mixture was stirred for 2 hours and then washed once with 10% aqueous sodium hydroxide solution and water, respectively. The organic layer was separated, dried with anhydrous sodium sulfate and then evaporated to obtain the title compound in the yield of 92%.

1. washwashed once with 10% aqueous sodium hydroxide solution and water
2. customThe organic layer was separated
3. dry with materialdried with anhydrous sodium sulfate
4. customevaporated