2-Pyridinyl-1,3-dioxolane → HCID 19047582, compound

HRID 1769055Notes

Reaction equation

HRID 1769055 reaction equation
[F:1][C:2]([F:12])([F:11])[C:3]1[CH:10]=[CH:9][C:6]([CH2:7][Br:8])=[CH:5][CH:4]=1.[O:13]1[CH2:17][CH2:16][O:15][CH:14]1[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][N:19]=1>>[Br-:8].[F:1][C:2]([F:12])([F:11])[C:3]1[CH:10]=[CH:9][C:6]([CH2:7][N+:19]2[CH:20]=[CH:21][CH:22]=[CH:23][C:18]=2[CH:14]2[O:13][CH2:17][CH2:16][O:15]2)=[CH:5][CH:4]=1

Participants

3

Reactant 2

HCID 797732-Pyridinyl-1,3-dioxolaneHCID 1230621-(Bromomethyl)-4-(trifluoromethyl)benzene

Product 1

HCID 19047582HCID 19047582, compoundYield 80.9%

Procedure

A mixture of 4.8 g (0.02 mol) of p-trifluoromethylbenzyl bromide and 3 g (0.019 mol) of 2-(1,3-dioxolan-2-yl)pyridine was allowed to stir at room temperature and then filtered. The solid residue was washed with ether and dried in vacuo to afford 6 g (76.9%) of 1-(p-trifluoromethylbenzyl)-2-(1,3-dioxolane-2-yl)pyridinium bromide (Formula IX: R1 =R7 =H; R2 =4--CF3 ; Z- =Br-).

Workup

  1. filtrationfiltered
  2. washThe solid residue was washed with ether
  3. customdried in vacuo

Sources & evidence

ORD record
ord-3d773b9735a54c9a80d1c2b1f5dc2a8f
Source dataset
uspto-grants-1995_01
Patent number
US05380729

Reaction notes

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