Potassium Carbonate → HCID 18947311, compound

Participants

Reaction Steps

1.98×10-2 mol of potassium carbonate, 1.33×10-2 mol of N-[2-(5-hydroxyindol-3-yl)ethyl]cyclopropylcarboxamide dissolved in 20 cm3 of anhydrous acetone, and 2.1×10-2 mol of 3-bromocyclohexene are introduced into a 50 cm3 flask with a ground neck. The mixture is heated under reflux for 22 hours. The reaction medium is filtered and the filtrate is evaporated under reduced pressure. Recrystallisation of the evaporation residue in ethyl acetate yields purified N-{2-[5-(cyclohexen-3-yloxy)indol-3yl]ethyl}-cyclopropylcarboxamide.

Provenance & Evidence