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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1769297Generated: October 26, 2026

4-Methyl-3-nitrobenzotrifluoride → 2-Methyl-5-(trifluoromethyl)aniline

https://huagongshe.com/reaction/1769297

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Methyl-3-nitrobenzotrifluorideHCID 1472885—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
Product2-Methyl-5-(trifluoromethyl)anilineHCID 273593379.9%

Reaction Steps

2-Methyl-5-trifluoromethylnitrobenzene (14.8 g) was dissolved in ethanol (100 ml) and hydrogenated at ambient temperature and pressure in the presence of palladium on charcoal (10%; 0.5 g). The solution was filtered and evaporated to dryness to give 2-methyl-5-trifluoromethylaniline (10.1 g) as a pale yellow oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05380865
Source datasetuspto-grants-1995_01
ORD IDord-a0521ef7ef064ea5981d79c5dc25bc44
Source noteuspto-grants-1995_01