HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Methyl-3-nitrobenzotrifluoride → 2-Methyl-5-(trifluoromethyl)aniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Methyl-3-nitrobenzotrifluoride | HCID 1472885 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-Methyl-5-(trifluoromethyl)aniline | HCID 2735933 | 79.9% |
Reaction Steps
2-Methyl-5-trifluoromethylnitrobenzene (14.8 g) was dissolved in ethanol (100 ml) and hydrogenated at ambient temperature and pressure in the presence of palladium on charcoal (10%; 0.5 g). The solution was filtered and evaporated to dryness to give 2-methyl-5-trifluoromethylaniline (10.1 g) as a pale yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05380865 |
| Source dataset | uspto-grants-1995_01 |
| ORD ID | ord-a0521ef7ef064ea5981d79c5dc25bc44 |
| Source note | uspto-grants-1995_01 |