Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1769348Generated: October 30, 2026

Methyl 3-[N-(p-Chlorobenzyl)-3-benzyl-5-(benzoyloxy)indol-2-yl]-2,2-dimethylpropanoate → 3-[N-(p-Chlorobenzyl)-3-benzyl-5-(quinolin-2-yl-methoxy)indol-2-yl]-2,2-dimethylpropanoic acid

https://huagongshe.com/reaction/1769348

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 3-[N-(p-Chlorobenzyl)-3-benzyl-5-(benzoyloxy)indol-2-yl]-2,2-dimethylpropanoateHCID 18947558—
ReactantMethyl 3-[N-(p-chlorobenzyl)-3-benzoyl-5-benzoyloxyindol-2-yl]-2,2-dimethylpropanoateHCID 18947606—
Product3-[N-(p-Chlorobenzyl)-3-benzyl-5-(quinolin-2-yl-methoxy)indol-2-yl]-2,2-dimethylpropanoic acidHCID 18947591—

Reaction Steps

The title compound was prepared under the conditions described in Step B and Step C of Example 9 but substituting the ester from Example 10 (Step A) for the ester of Example 9 (Step A), m.p. 178° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05380850
Source datasetuspto-grants-1995_01
ORD IDord-1cae7df4ca194a4b9d001e2cbb8a7838
Source noteuspto-grants-1995_01