Propionic Acid → HCID 18947576, compound

HRID 1769351Notes

Reaction equation

HRID 1769351 reaction equation
[Cl:1][C:2]1[CH:31]=[CH:30][C:5]([CH2:6][N:7]2[C:15]3[C:10](=[C:11]([O:16]C)[CH:12]=[CH:13][CH:14]=3)[C:9](SC(C)(C)C)=[C:8]2[CH2:23][C:24]([CH3:29])([CH3:28])[C:25]([OH:27])=[O:26])=[CH:4][CH:3]=1.[C:32](O)(=O)CC>>[Cl:1][C:2]1[CH:31]=[CH:30][C:5]([CH2:6][N:7]2[C:15]3[C:10](=[C:11]([OH:16])[CH:12]=[CH:13][CH:14]=3)[CH:9]=[C:8]2[CH2:23][C:24]([CH3:28])([CH3:29])[C:25]([O:27][CH3:32])=[O:26])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 1032Propionic AcidHCID 18947585HCID 18947585, compound

Product 1

HCID 18947576HCID 18947576, compound

Procedure

The title compound was prepared using methodology from Step A of Example 8 but substituting 3-[N-(p-chlorobenzyl)-3-(t-butylthio)-4-methoxy indol-2-yl]-2,2-dimethylpropanoic acid (Step B of Example 20) for the propanoic acid in Example 8 (Step A).

Sources & evidence

ORD record
ord-8482d3539fa34ab68bbee0b085fe73e0
Source dataset
uspto-grants-1995_01
Patent number
US05380850

Reaction notes

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