1,2-Difluoro-4-iodobenzene → 2-tert-Butyl-6-(3,4-difluoro-phenylethynyl)-pyrazolo[1,5-a]pyrimidine
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[n:6][n:7]2[c:8]([n:9][cH:10][c:11]([C:13]#[CH:14])[cH:12]2)[cH:15]1.[F:16][c:17]1[c:18]([F:24])[cH:19][c:20]([I:23])[cH:21][cH:22]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[n:6][n:7]2[c:8]([n:9][cH:10][c:11]([C:13]#[C:14][c:20]3[cH:19][c:18]([F:24])[c:17]([F:16])[cH:22][cH:21]3)[cH:12]2)[cH:15]1Participants
3
Sources & evidence
- ORD record
- ord-a0f1682da8c64bf7a2c832876a8a4815
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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