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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1769367Generated: October 29, 2026

Sodium → 3-[3-(4-Chlorobenzyl)-6-(quinolin-2-ylmethoxy)indol-2-yl]-2,2-dimethylpropanoic acid

https://huagongshe.com/reaction/1769367

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodiumHCID 5360545—
Reactant3-[1-(4-Chlorobenzyl)-3-(t-butylthio)-5-methoxyindol-2-yl]-2,2-dimethylpropanoic acid methyl esterHCID 11762500—
ReactantMethyl 3-[3-(4-chlorobenzyl)-6-(quinolin-2-ylmethoxy)indol-2-yl]-2,2-dimethylpropanoateHCID 18947534—
SolventWaterHCID 962—
Product3-[3-(4-Chlorobenzyl)-6-(quinolin-2-ylmethoxy)indol-2-yl]-2,2-dimethylpropanoic acidHCID 18947603—

Reaction Steps

The title compound was prepared using the conditions described in Step B of Example 1, but substituting the ester from Step D for the ester of Example 1, Step A. Anal. C, H, N for sodium salt 11/2 H2O Calc. C 65.75; H 5.33; N 5.11 Found. C 66.08; H 5.31; N 5.08.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05380850
Source datasetuspto-grants-1995_01
ORD IDord-87951d25b10f4bdab95dcf5773df202a
Source noteuspto-grants-1995_01