3-Bromotoluene → 2-(3-Methylphenyl)benzonitrile

HRID 1769404Notes

Reaction equation

Br[C:2]1[CH:3]=[C:4]([CH3:8])[CH:5]=[CH:6][CH:7]=1.Cl[C:10]1[CH:17]=[CH:16][CH:15]=[CH:14][C:11]=1[C:12]#[N:13]>>[C:12]([C:11]1[CH:14]=[CH:15][CH:16]=[CH:17][C:10]=1[C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([CH3:8])[CH:3]=1)#[N:13]

Participants

Reactant 2

HCID 115603-Bromotoluene

HCID 133912-Chlorobenzonitrile

Product 1

HCID 13942432-(3-Methylphenyl)benzonitrile

Procedure

In the same manner as in Example 2, 3-bromotoluene and 2-chlorobenzonitrile were reacted at 85° C. for 3 hours, and the reaction solution was analyzed by gas chromatography. The results are shown in Table 1.

Sources & evidence

ORD record: ord-583c4d41d6b349548432168fac1982a7
Source dataset: uspto-grants-1995_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05380910

Reaction notes

Loading…