HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → 6-ethyl-[1,2,5]oxadiazolo[3,4-d]pyrimidine-5,7(4H,6H)-dione-1-oxide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | 6-ethyl-8-nitrotetrazolo[1,5-c]pyrimidine-5,7(1H,6H)-dione | HCID 178462968 | — |
| Solvent | O-Xylene | HCID 7237 | — |
| Product | 6-ethyl-[1,2,5]oxadiazolo[3,4-d]pyrimidine-5,7(4H,6H)-dione-1-oxide | HCID 135795659 | 77% |
Reaction Steps
20.0 g of 6-ethyl-8-nitrotetrazolo[1,5-c]pyrimidine-5,7(1H,6H)-dione are heated at 120° C. for 7 hours with 200 ml of glacial acetic acid in 2000 ml of xylene. A small undissolved portion is filtered off, the filtrate is concentrated in vacuo and the oily residue is made to crystallise by trituration with methylene chloride. 13.5 g (77%) of 6-ethyl-[1,2,5]oxadiazolo[3,4-d]pyrimidine-5,7(4H,6H)-dione-1-oxide are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05382585 |
| Source dataset | uspto-grants-1995_01 |
| ORD ID | ord-e5caf30b569e4eda9af60ec0c493525d |
| Source note | uspto-grants-1995_01 |