HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 9947772, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2-Chloropyrimidine | HCID 74404 | — |
| Reactant | HCID 20097022 | HCID 20097022 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 9947772 | HCID 9947772 | — |
Reaction Steps
A mixture of 4.14 g (20 mmol) of 1-[4-(piperazinyl)-butyl)pyrrole, 2.29 g (20 mmol) of 2-chloropyrimidine and 4.1 g (30 mmol) of potassium carbonate in 60 ml of dimethylformamide is refluxed for 5 hours. The reaction mixture is evaporated under vacuum, chloroform is added and the mixture is washed with water, dried over sodium sulphate and evaporated under vacuum and 3.3 of 1-{4-[4-(2-pyrimidinyl)-1-piperazinyl]-butyl}pyrrole are obtained in the form of a liquid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05382586 |
| Source dataset | uspto-grants-1995_01 |
| ORD ID | ord-dd206a84ac6b4004ac0b29187a30d90c |
| Source note | uspto-grants-1995_01 |