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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1769613Generated: October 28, 2026

Potassium Carbonate → HCID 9947772, compound

https://huagongshe.com/reaction/1769613

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CarbonateHCID 11430—
Reactant2-ChloropyrimidineHCID 74404—
ReactantHCID 20097022HCID 20097022—
SolventDimethylformamideHCID 6228—
ProductHCID 9947772HCID 9947772—

Reaction Steps

A mixture of 4.14 g (20 mmol) of 1-[4-(piperazinyl)-butyl)pyrrole, 2.29 g (20 mmol) of 2-chloropyrimidine and 4.1 g (30 mmol) of potassium carbonate in 60 ml of dimethylformamide is refluxed for 5 hours. The reaction mixture is evaporated under vacuum, chloroform is added and the mixture is washed with water, dried over sodium sulphate and evaporated under vacuum and 3.3 of 1-{4-[4-(2-pyrimidinyl)-1-piperazinyl]-butyl}pyrrole are obtained in the form of a liquid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05382586
Source datasetuspto-grants-1995_01
ORD IDord-dd206a84ac6b4004ac0b29187a30d90c
Source noteuspto-grants-1995_01