m-Tolyl isocyanate → HCID 20097119, compound

Participants

Reaction Steps

The procedure is analogous to that described in Example 81, but 0.7 g of 2-amino-N-[2-(2,2-dimethylthiomorpholino)-2-oxoethyl]-N-phenylacetamide and 0.28 g of 3-methylphenyl isocyanate are used as the starting material. After recrystallization from an ethyl acetate/acetonitrile mixture (80/20 by volume), 0.6 g of N-[2-(2,2-dimethylthiomorpholino)-2-oxoethyl]-2-[3-(3-methylphenyl)ureido]-N-phenylacetamide melting at 186° C. is obtained.

Provenance & Evidence